The peninsula in rhytidoplasty

INTRODUCTION: High implantation of the hairline by the ear is a frequent, unpleasant stigma in rhytidoplasties.To overcome this problem, we created the Peninsula technique in the mid-1999.Initially used in secondary face liftings, its indication has since been broadened, becoming indispensable in primary cases of high hair implantation and in patie

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A Thomistic Account of Human Free Will and Divine Providence: Pedro de Ledesma and the De Auxiliis Controversy

Pedro de Ledesma is one of the Dominican theologians of the School of Salamanca involved in the De Auxiliis controversy, i.e., the disputes around a famous book by Luis de Molina on the relation between divine foreknowledge and providence and our free will.Studying an unpublished manuscript by Ledesma and his 1611 book on this subject, the article

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Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia

Summary: Monoallelic inactivation of CCCTC-binding factor (CTCF) in human cancer drives altered methylated genomic states, altered CTCF occupancy at promoter and enhancer regions, and deregulated global gene expression.In patients with T cell acute lymphoblastic leukemia (T-ALL), we find that acquired monoallelic CTCF-inactivating events drive subt

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